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Cambridge Global Challenges


The multidisciplinary research teams will lead projects that seek to address the health needs of women and children in disadvantaged populations globally. The awards will generate new evidence on interventions to tackle diseases that disproportionately affect women and their unborn children in low and middle-income countries, such as gestational diabetes mellitus, anaemia, hypertension and sexually transmitted diseases.

The projects will see research groups in Ethiopia, Uganda, the Gambia, Zambia and Nepal team up with researchers in India and the UK to ensure that results are implementable, scalable and in line with local policy needs, while also building capacity in these countries.

The following studies have now been awarded through the second phase of the initiative:

  • Pregnancy Interventions In Mothers Relating to Diabetes In Asian India and Low-income countries (The PRIMORDIAL Study)

UK lead: Fredrik Karpe, Oxford University
Indian lead: Jiji Mathews, Christian Medical College

  • Generating epidemiological, economic and attitudinal evidence to inform policy-making about HPV vaccine introduction in India and Ethiopia

UK lead: Edward Mulholland, London School of Hygiene and Tropical Medicine
Indian lead: Dr Narendea K Arora, The INCLEN Trust International

  • A cluster randomized trial of an mHealth integrated model of hypertension, diabetes and antenatal care in primary care settings in India and Nepal

UK lead: Oona Campbell, London School of Hygiene and Tropical Medicine
Indian lead:  Prof D Prabhakaran, Public Health Foundation of India

  • Comprehensive Anaemia Programme and Personalized Therapies (CAPPT)

UK lead: Sara Hillman, University College London
Indian lead: Vatsla Dadhwal, All India Institute of Medical Sciences

  • CRADLE-4: Can Reduction of Adverse pregnancy outcomes occur with planned DeLivery vs.Expectant management in pre-eclampsia

UK lead:  Andrew Shennan, King’s College London
Indian lead:  Shivaprasad S Goudar, KLE University’s Jawaharlal Nehru Medical College

  • Gestational diabetes in Uganda and India: Design and Evaluation of Educational Films for improving Screening and Self-management (GUIDES)

UK lead:  Sanjay Kinra, London School of Hygiene and Tropical Medicine
Indian lead:  Giridhara R Babu, Indian Institute of Public Health

  • A randomised controlled trial to compare two different doses of maternal B12 supplementation in improving infant B12 deficiency and neurodevelopment

UK lead: Monica Lakhanpaul, University College London
Indian lead:  Jitender Nagal, Sitaram Bhartia Inst of Science & Research.


To see the full press release, please visit the MRC website.

Cambridge Global Challenges is a Strategic Research Initiative of the University of Cambridge that aims to enhance the contribution of its research towards addressing global challenges and achieving the Sustainable Development Goals (SDGs) by 2030.

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