EDCTP Call: Advances in product development for effective prevention, treatment and management of co-infections and co-morbidities in Sub-Saharan Africa (EOI: 18th Oct 2018; full proposal by invitation: 28th March 2019)

The purpose of this call by the European & Developing Countries Clinical Trials Partnership (EDCTP) is to support actions that lead to improvements in the prevention, treatment and/or clinical management of co-infections and co-morbidities in sub-Saharan Africa, including at least one poverty-related disease (PRD).

Background

Co-infections with several pathogens are frequent in sub-Saharan Africa and represent an important public health problem in many areas due to accelerated and/or complicated disease progression, resulting in increased mortality and morbidity. These co-infections can result in unique challenges in treatment and prevention of disease, including increased drug toxicities and/or changes in efficacy of interventions.

The European & Developing Countries Clinical Trials Partnership (EDCTP) invites proposals for research that leads to advances in the development of new/improved products for the effective prevention, treatment and management of co-infections and co-morbidities.

 Objectives

Projects funded under this Call for Proposals should:

  • contribute towards the reduction of the number of cases of co-infections and co-morbidities in sub-Saharan Africa and thus contribute to achieving SDG 3 ‘Ensure healthy lives and promote well-being for all at all ages
  • advance products through the product development pipeline, and/or provide evidence to support label extension and/or be in line with EDCTP2’s strategic research agenda to be considered as having a higher impact.

Eligibility

Consortia comprising a minimum of three independent legal entities are eligible to apply. Two of the legal entities shall be established in two different European Partner States and one of the legal entities must be established in a sub-Saharan African country.

Level of funding

It is expected that 4-7 grants will share a call budget of €14 million for projects lasting 36-60 months.

For further details regarding PRDs within the remit of this call, eligible countries of origin and submission guidelines, please see the EDCTP website